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07/24/2009
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Document Type:
Grants Notice
Funding Opportunity Number:
RFA-CA-09-020
Opportunity Category:
Discretionary
Posted Date:
Jul 24, 2009
Creation Date:
Jul 24, 2009
Original Closing Date for Applications:
Oct 29, 2009
Current Closing Date for Applications:
Oct 29, 2009
Archive Date:
Nov 29, 2009
Funding Instrument Type:
Cooperative Agreement
Category of Funding Activity:
Education
Health
Category Explanation:
Expected Number of Awards:
Estimated Total Program Funding:
$3,000,000
Award Ceiling:
Award Floor:
CFDA Number(s):
93.393
--
Cancer Cause and Prevention Research
93.394
--
Cancer Detection and Diagnosis Research
Cost Sharing or Matching Requirement:
No
Eligible Applicants
Public and State controlled institutions of higher education
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Private institutions of higher education
For profit organizations other than small businesses
Small businesses
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Additional Information on Eligibility:
Other Eligible Applicants include the following:
Eligible Agencies of the Federal Government; U.S. Territory or Possession.
Agency Name
National Institutes of Health
Description
Purpose. This funding opportunity announcement (FOA) solicits cooperative agreement applications for a Data Management and Coordinating Center (DMCC) and a Statistics and Biomarker Resource Center (SBRC) as components of the Early Detection Research Network (EDRN). EDRN is a national consortium funded to discover, develop, and validate biomarkers for early cancer detection, risk assessment and the molecular diagnosis and prognosis of early cancer. Statistical and informatics activities for the EDRN are divided between the DMCC and the SBRC, as follows. The DMCC supports statistical and computational analysis, data management and protocol development, and informatics infrastructure and coordinates network-wide meetings and conferences. Its responsibilities are: (1) Network Coordination, (2) Data Management and Protocol Development, (3) Theoretical and Applied Statistical Research, and (4) Validation Infrastructure and Services. The SBRC is responsible for providing statistical services and consultation to EDRN investigators on study design and protocol development of individual EDRN studies and functions as the content management center for the EDRN biomarker knowledgebase. The other three main components of the EDRN are the Biomarker Developmental Laboratories (BDLs), the Clinical Validation Centers (CVCs), and the Biomarker Reference Laboratories (BRLs).
Mechanism of Support. This FOA utilizes the NIH Cooperative Agreement (U24) award mechanism. Parallel FOAs for other EDRN components include RFA-CA-09-017 (U01) for BDLs, RFA-CA-09-018 (U01) for CVCs, and RFA-CA-09-019 (U24) for BRLs.