The synopsis for this grant opportunity is detailed below, following
this paragraph. This synopsis contains all of the updates to this
document that have been posted as of
10/29/2009
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Document Type:
Grants Notice
Funding Opportunity Number:
PAR-10-016
Opportunity Category:
Discretionary
Posted Date:
Oct 29, 2009
Creation Date:
Oct 29, 2009
Original Closing Date for Applications:
Jan 10, 2010
Current Closing Date for Applications:
Jan 10, 2010
Archive Date:
Feb 10, 2010
Funding Instrument Type:
Grant
Category of Funding Activity:
Education
Environment
Health
Category Explanation:
Expected Number of Awards:
Estimated Total Program Funding:
Award Ceiling:
$200,000
Award Floor:
CFDA Number(s):
93.113
--
Environmental Health
93.393
--
Cancer Cause and Prevention Research
Cost Sharing or Matching Requirement:
No
Eligible Applicants
State governments
Public and State controlled institutions of higher education
Native American tribal governments (Federally recognized)
Native American tribal organizations (other than Federally recognized tribal governments)
Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
Private institutions of higher education
For profit organizations other than small businesses
Small businesses
Others (see text field entitled "Additional Information on Eligibility" for clarification)
Additional Information on Eligibility:
Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Agency Name
National Institutes of Health
Description
Purpose. This Funding Opportunity Announcement (FOA) is designed to support multidisciplinary teams to develop enabling technologies that will facilitate and stimulate translation of basic research in DNA damage and repair to human population or clinical studies. These projects will develop new tools to measure global DNA repair capacity in individuals or responses in individual DNA repair pathways activated in response to DNA damaging agents. The assays are expected to enable the study of DNA damage response in exposed individuals in clinical and epidemiological studies. Thus, a key goal is the identification and verification of reproducible biomarkers that indicate the levels of specific repair activity or mutagenic outcomes and would provide the basis for assay development. Field or pilot testing of tools or assays is encouraged. Support will be provided for the development of novel assays for detecting DNA damage and repair or for improving existing measures. It is expected that these improved technologies will be appropriate and scalable for epidemiological and clinical studies.
Mechanism of Support. This FOA will use the NIH Exploratory/Developmental (R21) grant mechanism.
Funds Available and Anticipated Number of Awards. Awards issued under this FOA are contingent upon the availability of funds and the submission of a sufficient number of meritorious applications.
Budget and Project Period: The total project period for an application submitted in response to this funding opportunity may not exceed two years. For an R21, direct costs are limited to $275,000 over a two-year period, with no more than $200,000 in direct costs allowed in any single year.
